I use IPv6 exclusively for my homelab. The pros:
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No more holepunching kludge with solutions like ZeroTier or Tailscale, just open a port and you are pretty much good to go.
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The CGNAT gateway of my ISP tends to be overloaded during the holiday seasons, so using IPv6 eliminates an unstability factor for my lab.
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You have a metric sh*t ton of addressing space. I have assigned my SSH server its own IPv6 address, my web server another, my Plex server yet another, … You get the idea. The nice thing here is that even if someone knows about the address to my SSH server, they can’t discover my other servers through port scanning, as was typical in IPv4 days.
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Also, because of the sheer size of the addressing space, people simply can’t scan your network.
If proper SATA ever goes away, I’d wager that there will still be SATA-to-USB adapters on sale. Heck, people still find ways to connect floppy drives to their modern PCs.